2024-03-11 17:44:43,328 [INFO] Running /home/mshokrof/miniconda3/bin/truvari bench -b /home/mshokrof/NistSV/HG002_SVs_Tier1_GRCH38.vcf.gz -c manta.HG002.vcf.gz --includebed /home/mshokrof/NistSV/HG002_SVs_Tier1_v0.6.GRCh38.bed -o truvari_output_manta --passonly -r 2000 -C 3000 --reference /group/ctbrowngrp/mshokrof/GRCh38_full_analysis_set_plus_decoy_hla.fa 2024-03-11 17:44:43,328 [INFO] Params: { "base": "/home/mshokrof/NistSV/HG002_SVs_Tier1_GRCH38.vcf.gz", "comp": "manta.HG002.vcf.gz", "output": "truvari_output_manta", "reference": "/group/ctbrowngrp/mshokrof/GRCh38_full_analysis_set_plus_decoy_hla.fa", "giabreport": false, "debug": false, "prog": false, "refdist": 2000, "unroll": false, "pctsim": 0.7, "minhaplen": 50, "pctsize": 0.7, "pctovl": 0.0, "typeignore": false, "dup_to_ins": false, "use_lev": false, "chunksize": 3000, "gtcomp": false, "bSample": null, "cSample": null, "sizemin": 50, "sizefilt": 30, "sizemax": 50000, "passonly": true, "no_ref": false, "includebed": "/home/mshokrof/NistSV/HG002_SVs_Tier1_v0.6.GRCh38.bed", "extend": 0, "multimatch": false } 2024-03-11 17:44:43,328 [INFO] Truvari version: 3.5.0 2024-03-11 17:44:44,176 [INFO] Including 34811 bed regions 2024-03-11 17:44:44,602 [INFO] Found 1 chromosomes with overlapping regions 2024-03-11 17:44:58,189 [INFO] Zipped 26899 variants Counter({'base': 19922, 'comp': 6977}) 2024-03-11 17:44:58,189 [INFO] 9740 chunks of 26899 variants Counter({'__filtered': 12089, 'base': 9570, 'comp': 5240}) 2024-03-11 17:44:58,191 [INFO] Stats: { "TP-base": 3698, "TP-call": 3698, "FP": 1160, "FN": 5872, "precision": 0.7612186084808563, "recall": 0.3864158829676071, "f1": 0.5126143609647907, "base cnt": 9570, "call cnt": 4858, "TP-call_TP-gt": 3550, "TP-call_FP-gt": 148, "TP-base_TP-gt": 3550, "TP-base_FP-gt": 148, "gt_concordance": 0.9599783666846944, "gt_matrix": { "(0, 1)": { "(0, 1)": 1859, "(1, 1)": 108 }, "(1, 1)": { "(1, 1)": 1691, "(0, 1)": 40 } } } 2024-03-11 17:44:58,251 [INFO] Finished bench